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Abstract

Surgical site infections (SSIs) are a global healthcare challenge. The Pseudomonas aeruginosa is a significant SSI pathogen with the oprL gene conferring its multidrug resistance. Although extensive studies on pathogens in infection control are recommended, a study of this kind has not been conducted in Bauchi, Nigeria.


Objectives: This study determined the prevalence and associated factors for SSIs linked with P. aeruginosa with oprL gene. Surgical site swabs (n=250) collected from two hospitals in Bauchi, Nigeria, were cultured on Cetrimide agar to isolate P. aeruginosa. The oprL genes of the isolates were detected through a Polymerase chain Reaction. Chi-square tests, Fisher's exact test, and binary logistic regression analyzed the association between SSIs and other variables. About 2% (5/250) of the swabs were infected with P. aeruginosa with oprL gene. SSI occurrence was statistically associated with post-operative duration (p = 0.01). Prolonged postoperative periods increased the odds of developing SSIs by a factor of 3.81 (O.R.:3.81, p=0.02). No significant associations were found between SSIs and sex (p = 0.65), age (p = 0.09), surgery (p = 0.06), and HIV status (p = 0.31). The prevalence of P. aeruginosa linked to SSIs was low. Prolonged postoperative care significantly increased the risk of SSIs. Future research with longitudinal designs and large samples will monitor additional risk factors of SSIs. Infection control should emphasize post-operative care for SSIs.The integration of molecular confirmation of P. aeruginosa isolates should be routine in SSI management.

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Infection Surgical Site Pseudomonas Prevalence Pathogen Nigeria

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Author Biography

T Onyi, Department of Community Medicine, Abubakar Tafawa Balewa University, Bauchi, Nigeria

Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria

How to Cite
Onyi, T., Doko, M. H. I., & Ella, E. E. (2024). Prevalence, Distribution, and Associated Factors of Surgical Site Infections Linked to <i>Pseudomonas aeruginosa</i> with oprL Virulence Gene in Bauchi, Nigeria. Journal of Public Health and Toxicological Research, 2(2), 86–96. https://doi.org/10.60787/jphtr.vol2no2.35
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