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Abstract

Antibiotic misuse is a driver for antimicrobial resistance in resource-limited settings with unrestricted access. The objective of this study is to examine the knowledge of antibiotics and the prevalence of antibiotic misuse among paediatric caregivers in two healthcare facilities in Benin City. A descriptive cross-sectional study was conducted among 262 paediatric caregivers who visited Central Hospital and University of Benin Teaching Hospital during the study period using a standardized questionnaire. Data were analyzed with SPSS version 22 using descriptive statistics. About half [144 (47.3%)] of the pediatrics caregivers had poor knowledge of antibiotics. Paediatric caregivers in rural areas had poor knowledge 32 (22.2%), compared with those in urban settings, 93 (87.8%), p=0.01. Antibiotic misuse was high [216 (82.8%)] across both health facilities. No socio-demographic factor was found to be associated with misuse of antibiotics. Most commonly misused antibiotics were amoxicillin [155(59%)] and metronidazole [142(54%)] used for symptoms such as fever [183(70%)] and cough [127 (45.8%)]. Antibiotic knowledge was found to be average, but misuse of antibiotics was high in both healthcare facilities. Education on appropriate use of antibiotics can start from healthcare institutions targeting paediatric caregivers, which can be upscaled towards the public.

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Knowledge Antibiotic Misuse Paediatric Caregivers

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Aika, I., & Oseji, F. (2026). A Study of Knowledge of Antibiotics and Misuse among Paediatric Caregivers Visiting Two Healthcare Facilities in Nigeria. Journal of Public Health and Toxicological Research, 3(3), 281–288. https://doi.org/10.71637/jphtr.vol3no3.62
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References

  1. Abiola, A. O., Oluwole, E. O., Oredipe, O. A., & Abdulkareem, A. T. (2023). Knowledge, attitude and practice of antibiotic use among residents of a community in South-West Nigeria. West African Journal of Pharmacy, 31(1), 80–91. https://doi.org/10.60787/wapcp-31-1-203
  2. Aderonke O. Oluwo, Mary A. Lawal, Cecilia A. Mabogunje, Olubunmi T. Okurame. (2024). Antibiotic susceptibility pattern among children admitted to a hospital in Nigeria: A retrospective study.
  3. Akande-Sholabi W, Oyesiji E. Antimicrobial stewardship: knowledge, perceptions, and factors associated with antibiotics misuse among consumer's visiting the community pharmacies in a Nigeria Southwestern State. J Pharm Policy Pract. 2023 Oct 11;16(1):120. doi: 10.1186/s40545-023-00629-x. PMID: 37821920; PMCID: PMC10566051.
  4. Akinlade KA, Akinyemi JO, Fawole OI. Knowledge of hazards of antibiotics self-medication by mothers for under-fives in rural community of South-west Nigeria. Afr J Med Med Sci. 2015;44(4):303–9.
  5. Allwell-Brown G, Hussain-Alkhateeb L, Sewe MO, Kitutu FE, Strömdahl S, Mårtensson A, et al. Determinants of trends in reported antibiotic use among sick children under five years of age across low-income and middle-income countries in 2005–17: A systematic analysis of user characteristics based on 132 national surveys from 73 countries. Int J Infect Dis. 2021;108:473–82. [cited 2022 Feb 10] Available from: https://www.sciencedirect.com/science/article/pii/S1201971221004604
  6. Auta A, Banwat SB, David S, Dangiwa DA, Ogbole E, TorAnyiin AJ. Antibiotic use in some Nigerian communities: Knowledge and attitudes of consumers. Trop J Pharm Res. 2013;12:1087–92.
  7. Belachew SA, Hall L, Selvey LA. Non-prescription dispensing of antibiotic agents among community drug retail outlets in Sub-Saharan African countries: a systematic review and meta-analysis. Antimicrob Resistance Infect Control. 2021;10(1):13. [cited 2022 Feb 12] Available from: https://doi.org/10.1186/s13756-020-00880-w
  8. Burstein VR, Trajano RP, Kravitz RL, Bell RA, Vora D, May LS. Communication interventions to promote the public’s awareness of antibiotics: a systematic review. BMC Public Health. 2019;19(1):899. [cited 2022 Jul 5] Available from: https://doi.org/10.1186/s12889-019-7258-3
  9. Collignon P. Antibiotic resistance: Are we all doomed? Intern Med J. 2015;45(11):1109–1115.
  10. Ekong U, Ekpo L, Okpokowuruk F, Uhegbu K, Igri E. Antibiotic Use in Home Treatment of Childhood Diarrhoea in Uyo, Nigeria. (2024). Nigerian Journal of Paediatrics, 51(2), 85–92. https://doi.org/10.4314/
  11. Federal Republic of Nigeria: Nigeria Centre for Disease Control. Federal Ministries of Agriculture and Rural Development, Environment and Health; Global Antibiotic Resistance Partnership Project. In: Antimicrobial Use and Resistance in Nigeria: Situation Analysis and Recommendations. Nigeria: Nigeria Centre for Disease Control; 2017.
  12. Hambal I. Salihu Dadari. Antibiotics use, knowledge and practices on antibiotic resistance among breastfeeding mothers in Kaduna State (Nigeria). Journal of Infection and Public Health. Volume 13, Issue 12, December 2020, Pages 2072–2079. https://doi.org/10.1016/j.jiph.2019.05.008
  13. Islam, M.W., Shahjahan, M., Azad, A.K. et al. Factors contributing to antibiotic misuse among parents of school-going children in Dhaka City, Bangladesh. Sci Rep. 14, 2318 (2024). https://doi.org/10.1038/s41598-024-52313-y
  14. Leopold SJ, van Leth F, Tarekegn H, Schultsz C. Antimicrobial drug resistance among clinically relevant bacterial isolates in sub-Saharan Africa: a systematic review. J Antimicrob Chemother. 2014;69(9):2337–53. [cited 2022 Feb 10] Available from: https://doi.org/10.1093/jac/dku176
  15. MacGowan A, Macnaughton E. (2017). Antibiotic Resistance. Medicines, 45(100):622–628.
  16. Nigeria Centre for Disease Control [Internet]. Antimicrobial Resistance in Nigeria. Available from: http://ncdc.gov.ng/training/nfeltp%0Ahttp://www.ncdc.gov.ng/ncdc. [Accessed December 2025].
  17. Ofori-Asenso R, Agyeman AA. Irrational use of medicines-a summary of key concepts. Pharmacy (Basel). 2016;4(4):35. https://doi.org/10.3390/pharmacy4040035
  18. Okide CC, Grey-Ekejiuba O, Ubaka CM, Schellack N, Okonta M. Parents' knowledge, attitudes and use of antibiotics in upper respiratory infections in Nigerian children. Afr J Biomed Res. 2020;23:213–20.
  19. Okide CC, Grey-Ekejiuba O, Ubaka CM, Schellack N, Okonta M. Parents' knowledge, attitudes and use of antibiotics in upper respiratory infections in Nigerian children. Afr J Biomed Res. 2020;23:213–20.
  20. Popoola O, Adepitan D, Adeyemi A, Oladeru O, Yusuff S. A national survey of the antibiotic use, self-medication practices, and knowledge of antibiotic resistance among graduates of tertiary institutions in Nigeria. Scientific African. Volume 23, 2024, e01978. https://doi.org/10.1016/j.sciaf.2023.e01978
  21. Uchendu UO, Ikefuna AN, Emodi J. Medication use and abuse in childhood diarrhoeal diseases by care-givers reporting to a Nigerian tertiary health institution. SA J Child Health. 2009;3:83–9.
  22. Wonodi W, and Boma A. (2024). Pre-Hospital Antibiotic Use in the Rivers State University Teaching Hospital Paediatric Outpatient Clinic. International Journal of Tropical Disease & Health. 45(9):45–53. https://doi.org/10.9734/ijtdh/2024/v45i91588
  23. World Health Organization. Global action plan on antimicrobial resistance. WHO Press. (2015), pp. 1–28. Available from: http://www.who.int/drugresistance/global_action_plan/en/. [Accessed December 2025].
  24. World Health Organization. Stop Overuse and Misuse of Antibiotics: Combat Resistance. Available from: https://www.who.int/westernpacific/news/detail/10-11-2017-stop-overuse-and-misuse-of-antibiotics-combat-resistance [Last accessed on Dec 2025].
  25. Zewdie S, Kassa AA, Bizuneh MM, Tesfaye TC, Yayehrad AT. Antibiotic use without prescription among children aged under 5 years in low- and middle-income countries: a systematic review and meta-analysis. JAC Antimicrob Resist. 2025 Jun 6;7(3):dlaf093. doi: 10.1093/jacamr/dlaf093. PMID: 40487188; PMCID: PMC12142460.